I don't see any real issues
especially if it has a good hot ignition system,
good distributor with the proper curve, advance restrictions
{& use an adj. vacuum advance for the street, some might suggest too}
some quality low ohm resistance wires, the proper heat range plugs &
the carb is "actually tuned properly"
jetted, proper size air bleeds/emulsion tube/idle circuit jets
the proper color/size accel. pump cam & discharge nozzles etc.
with a single plane or a newer Dominator
I doubt it'll be a bolt on & run fine, out of the box {you my get lucky}
IMO it'll need tuning & tinkering, maybe even
some dyno or track time to get it perfect...
Your camshaft choice & your converter selection
will probably dictate how "cantankerous" or "drivable"
it may actually be, just make sure you keep it cool,
have fresh cool dense air not under hood heated air &
has plenty of fuel supply....
Kind of basic performance 101 stuff...
If you don't have any books on tuning the carb & ignition properly,
I'd suggest that you get one, learn the ins & out of them both...
1st Before you do your build, it'll be money well spent...
good luck