Well, it would be a project. First, you'd have to adapt it to the firewall. Mounting studs, hangers, and matching up the fresh air duct, and more holes for the evaporator and heater core. Is your car already AC equipped? Then you'd have to figure out controls. Much of the newer stuff you mentioned is tied into the CAN buss of other aspect of the body control, the actuators are electric, some cycle at every start to verify feedback position, etc. You'd need a similar sized system - a Neon evaporator and metering device from a car with relatively "tight" weatherstripping and cabin air infiltration may not cool a 69 B body with whistling windows.
On the other hand, a size-matched system from the 134a era is likely well sorted as a package - you could achieve good performance more efficiently the the power-eating RV2 piston compressors.
In the end, the effort may equal the Classic Air retrofit system that uses the original A/C box with newer under hood parts.