Assuming you have total choice on 400 production blocks? (Which of course is highly unlikely today?) The 400 "230" date stamp prior to Oct 1971 were said to have strongest web cast for the 400 block. While 630s had the thickest cylinder walls.
I believe the older 230 block with stronger bottom end webbing is the most desirable block for a stroker build. If one was building a shorter stroked high Rev turbo build? Thicker cylinder walls would certainly be more beneficial. But what ever block is used? And as 4mulas outlined? Block condition will dictate the machining requirements. The true "451" build is a blocked bored .035 over. I liked/use Ross 4.375" piston (Stock 400 4.34 + .035 over bore)
https://www.rosspistons.com/product...lat-top-4-375-bore-3-750-stroke-3-50cc-99494/
Unless your block prep required heavy deck machining to clean? Your head gasket choice will be dictated by any deck work. And desired final static compression. (For street pump gas? 10.0:1 is about as high I would suggest unless more aggressive quench and head work is considered.) Stock length 6.7" rods. After market rods of course will provide greater strength and performance longevity. (Consider aluminum rods if budget allows?) I found a set of BME rods on their over stock list from their site for $500 about 3 years ago.
http://www.bmeltd.com/rodoverstocksale.htm
Heads is the next step. I would highly recommend aluminum. By the time you get old irons machined any where near today's aluminum just out of the box? You still have heavier and older heads that are more likely to wear and fail. JMO. What head? And cc? Your desired compression build will narrow that decision. Indy or Eddys can both easily get you to your street build.
Then fuel and air delivery. And of course today has many options. The EFI systems are nice. But spendy. And do require a new learning curve. But that doesn't mean be afraid. Personally? I would still go with a single 4 barrel and performance intake? (My advice? Use the smallest carb that can deliver the CFMs your engine requires?)
I am a strong believer that cam profile choice should be last for consideration. If I was building for near all street? I would consider a hydraulic roller. Stroker engines typically struggle for high RPM anyways. So build to 6500 RPM redline. Give block/heads and fuel/air induction system configuration to comp cams? And have them custom grind a cam for your build and application.
Converter and drivetrain considerations are now dictated by your engine output to the vehicle chassis setup. Including vehicle weight and tire requirements/choice.
But in my opinion? It starts with the block bottom end.