The transmission crossmember needs to be modified, and where the T-bar brace goes up into the trans tunnel, it needs to be cut back and reinforced.
All the OD transmissions have the small block bellhousing setup, but can be adapted to a big block using the JW Performance Ultra Bell adaptor:
92457 / Ultra-Bell Big Block Chrysler to TF727 or A518
The ultra-bell, you cut the small block bellhousing off at the pump, and the new bellhousing bolts to the transmission at the pump.
JVX also sells a adaptor plate, but it moves everything back 1/2" and you have to cut the stock bellhousing for the starter.
The RH (Hydraulic Governor) is the most common as it will shift 1-3 like a 727, and only electronics are lockup and overdrive.
The RE (Electronic) you will need electronics to read the output shaft (electronic speedometer) sensor, and the pulse width modulate the governor pressure solenoid to increase pressure with output shaft speed. The transmission had a pressure sensor at the solenoid so the electronics can check the pressure is raising with speed correctly to get the 123 shift points.