I use to use a lot of Lunati stuff, prior to 2007
I had decent luck with them
I have custom ground Crane stuff, in my current cars
2005 (IIRC) just before the S&S buyout,
they still have a great staff
Crane use to be a loyal sponsor too,
so it's sort of payback/pay forward deal
I knew a few with Isky stuff, I usually beat regularly too

(probably not because of their camshaft choices either)
I also had use some Isky's way back in the day
probably 1980's, mostly BBC & SBC's, I never had a real issue,
none of it, not out of the norm for racecars anyway
**** happens, can't always blame it on the parts or suppliers
good luck